Top 5 Best Supplements To Increase Progesterone

Explore supplements to increase progesterone, including vitamin B6, magnesium, zinc, and herbal options to support women's hormonal and reproductive health.

1 Clean Nutraceuticals
Clean Nutraceuticals
Supports Healthy Progesterone Levels Naturally
  • Supports Hormonal Health and Wellness Naturally

  • Combines DHEA and Pregnenolone Support

  • Includes DIM Ashwagandha and Boron

  • Provides Essential Vitamins and Minerals

4.4
1006 reviews
30% OFF

1K+ bought in past month

2 Equilife
Equilife
Promotes Women's Reproductive Health Support
  • Supports Women's Menopausal Wellness Naturally

  • Features Black Cohosh and Passionflower

  • Promotes Healthy Menstrual Cycle Support

  • Non-GMO, Dairy-Free, Soy-Free Formula

4.4
169 reviews
30% OFF

100+ bought in past month

3 Life Extension
Life Extension
Supports Hormonal Balance and Wellness
  • Supports Memory and Cognitive Health

  • Provides 100 mg Pregnenolone Per Capsule

  • Supports Focus and Mental Clarity

  • Gluten-Free, Non-GMO Supplement Formula

4.6
4059 reviews
50% OFF

4K+ bought in past month

4 Birthright
Birthright
Encourages Healthy Menstrual Cycle Function
  • Supports Women's Hormonal Wellness Naturally

  • Promotes Healthy Menstrual Cycle Support

  • Includes Magnesium and Red Raspberry

  • Supports Ovulation and Daily Energy

4.6
46 reviews
40% OFF

50+ bought in past month

5 VH Nutrition
VH Nutrition
Supports Overall Female Hormonal Wellness
  • Supports Healthy Estrogen Metabolism Naturally

  • Promotes Women's Hormonal Balance Support

  • Provides Convenient Daily Capsule Supplementation

  • Designed for Women's Hormonal Wellness

4.2
7894 reviews
30% OFF

7K+ bought in past month

Top 5 Best Supplements To Increase Progesterone

Best Supplements To Increase Progesterone include products formulated to support women's hormonal and reproductive wellness. Ingredients such as magnesium, vitamin B6, and selected herbal extracts are commonly used in hormone support supplements. However, scientific evidence varies, and supplements cannot reliably increase progesterone levels. Consult a healthcare professional before starting supplementation.

1. Clean Nutraceuticals

Clean Nutraceuticals
DHEA 200mg Supplement Pregnenolone 100mg for Men & Women
Best Natural Supplements for Progesterone Support

Clean Nutraceuticals offers multi-ingredient supplements designed to support hormonal wellness in adults. Its DHEA and pregnenolone complex combines hormone-related compounds with ingredients such as DIM, ashwagandha, boron, and essential vitamins and minerals. Before using this type of supplement, consult a healthcare professional because DHEA and pregnenolone can affect hormone levels.

Clean Nutraceuticals DHEA 200 mg and Pregnenolone 100 mg Complex is a multi-ingredient supplement formulated to support hormonal wellness and overall nutritional health in adult men and women. Each serving combines DHEA and pregnenolone with DIM, ashwagandha, boron, calcium, magnesium, zinc, and vitamin D3. The product comes in a bottle containing 60 capsules, providing 30 servings according to the product details. It is marketed for energy, vitality, and general wellness, but because it contains hormone precursors and high-dose nutrients, professional guidance is important before use.

Benefits

This Clean Nutraceuticals formula combines hormone-related compounds, botanical ingredients, and essential nutrients in one supplement.

  • Provides 200 mg DHEA per serving
  • Includes 100 mg pregnenolone per serving
  • Combines multiple hormone-support ingredients
  • Contains DIM and ashwagandha
  • Provides 6 mg boron
  • Includes calcium and magnesium
  • Contains 50 mg zinc
  • Provides 5,000 IU vitamin D3
  • Offers a convenient capsule format
  • Designed for adult men and women

How It Works

Clean Nutraceuticals combines several ingredients that perform different functions in the body. DHEA and pregnenolone are hormone precursors, while DIM is a compound associated with estrogen metabolism pathways. Ashwagandha is an herbal ingredient studied for potential stress-related benefits. Zinc, magnesium, calcium, and vitamin D3 contribute to normal physiological functions, including immune health, muscle function, and bone maintenance.

  • DHEA: A hormone precursor involved in the production of androgens and estrogens.
  • Pregnenolone: A steroid hormone precursor involved in the body's hormone production pathways.
  • DIM: A compound derived from substances found in cruciferous vegetables and studied for its effects on estrogen metabolism.
  • Ashwagandha: An herb studied for potential effects on perceived stress and sleep.
  • Boron: A trace element investigated for its role in bone and mineral metabolism.
  • Calcium: Helps maintain normal bones, teeth, and muscle function.
  • Magnesium: Supports normal nerve function, muscle function, and energy metabolism.
  • Zinc: Contributes to immune function, DNA synthesis, and normal cell division.
  • Vitamin D3: Supports calcium absorption and healthy bone maintenance.

These ingredients serve different purposes, and their combination does not establish that the product will balance hormones, improve physical performance, or increase energy in every user.

Product Overview Table

FeatureDetails
BrandClean Nutraceuticals
Product NameDHEA 200 mg and Pregnenolone 100 mg Complex
Primary Supplement TypeDHEA Supplement
Main IngredientsDHEA, pregnenolone, DIM, ashwagandha
DHEA Amount200 mg per serving
Pregnenolone Amount100 mg per serving
Boron Amount6 mg
Zinc Amount50 mg
Vitamin D3 Amount5,000 IU
Additional NutrientsCalcium and magnesium
FormCapsules
Capsule Count60 Capsules
Servings per Container30
FlavorNatural
Intended UsersAdults, according to product labeling
Manufacturing ClaimManufactured in the USA with globally sourced ingredients, according to the manufacturer

Why Choose This Hormone Support Supplement

This Clean Nutraceuticals formula may interest adults comparing multi-ingredient products for hormonal wellness. It combines hormone precursors with botanical ingredients and several vitamins and minerals in a single product. However, its high doses mean it should not be treated like an ordinary multivitamin.

  • Combines DHEA and pregnenolone
  • Includes DIM and ashwagandha
  • Provides multiple vitamins and minerals
  • Offers 60 capsules per bottle
  • Combines hormone precursors and nutrients
  • Designed for adult wellness routines
  • Includes vitamin D3 and calcium
  • Provides zinc and magnesium in one formula

Important Safety Considerations

This product contains substantial doses of hormone precursors and nutrients. The stated 200 mg of DHEA per serving is a high dose, and the 50 mg of zinc exceeds the adult tolerable upper intake level of 40 mg per day established in the United States for routine total intake. Long-term excessive zinc intake can contribute to copper deficiency and other adverse effects.

DHEA and pregnenolone can affect hormone levels and may cause acne, changes in mood, or other hormone-related side effects. They may be unsuitable for people with hormone-sensitive conditions and can interact with medications. Vitamin D3 at 5,000 IU also exceeds the general adult upper intake level of 4,000 IU per day established in the United States unless a clinician recommends otherwise.

Consult a qualified healthcare professional before using this product, especially if you have a medical condition, take prescription medication, or are pregnant or breastfeeding. Do not assume that a high-dose hormone supplement is necessary for maintaining healthy hormone levels.

2. Equilife

Equilife
Equilife Progesterone Support for Women, Non GMO Herbal Blend
Top Supplements for Healthy Progesterone Levels

Equilife Progesterone Support for Women is a herbal supplement formulated with black cohosh and passionflower. It is marketed to support menopausal wellness, mood, and menstrual cycle health. The formula is non-GMO and free from dairy, soy, and gluten. However, it is not proven to increase progesterone levels, so professional advice is recommended.

Equilife Progesterone Support for Women is a botanical supplement designed to support women's hormonal wellness, menstrual health, mood, and comfort during hormonal transitions. This herbal blend features black cohosh, chaste tree, coleus forskolin, dong quai, and passionflower extract in a convenient 90-capsule bottle. The formula is marketed for women experiencing menopause-related discomfort, mood changes, and menstrual concerns. It is labeled vegan, non-GMO, gluten-free, and free from dairy and soy, making it an option for adults seeking plant-based support for their wellness routine.

Benefits

Equilife Progesterone Support combines traditional botanical ingredients to support general women's wellness during different stages of hormonal change.

  • Supports women's hormonal wellness routines
  • Contains black cohosh botanical extract
  • Includes chaste tree and passionflower
  • Supports menstrual wellness and comfort
  • Designed for menopause-related wellness support
  • Supports mood and everyday well-being
  • Features a plant-based herbal blend
  • Vegan-friendly and non-GMO formula
  • Gluten-free, dairy-free, and soy-free
  • Convenient 90-capsule bottle

How It Works

Equilife combines several botanical ingredients traditionally used in women's wellness products. Some ingredients, including black cohosh and chaste tree, have been studied for potential effects on particular menopause or menstrual symptoms. However, research findings are mixed, and evidence that this combination increases progesterone levels or treats hormonal imbalances is insufficient.

  • Black cohosh: Studied for possible effects on menopause-related symptoms, although results are inconsistent.
  • Chaste tree: Traditionally used for menstrual symptoms, with limited evidence for certain uses.
  • Passionflower: An herb studied for potential calming effects.
  • Dong quai: Used in traditional herbal practices for women's health, but strong evidence for its effectiveness is lacking.
  • Coleus forskolin: Contains forskolin, a compound studied for several biological effects, though evidence for weight management and hormonal benefits is limited.

These ingredients serve different purposes, and their combined presence does not guarantee improvements in mood, energy, menstrual regularity, or progesterone levels. The product should not replace medical assessment for persistent symptoms.

Product Overview Table

FeatureDetails
BrandEquilife
Product NameProgesterone Support for Women
Supplement TypeHerbal Supplement
Main IngredientBlack Cohosh
Additional IngredientsChaste tree, coleus forskolin, dong quai, passionflower
FormCapsules
Capsule Count90 Capsules
FlavorUnflavored
Diet TypeVegan, Vegetarian, Plant-Based
Other FeaturesNon-GMO, Gluten-Free
Free FromDairy and Soy, according to the product description
Primary FocusWomen's Hormonal and Menstrual Wellness
Intended UsersAdults
Suggested UseUp to 3 capsules daily or as directed by a qualified healthcare practitioner

Why Choose Equilife Progesterone Support

Equilife Progesterone Support may appeal to women looking for a multi-ingredient herbal supplement rather than a single botanical product. Its plant-based formulation combines several traditional herbs in a convenient capsule format.

  • Multi-ingredient botanical wellness formula
  • Features black cohosh and chaste tree
  • Includes passionflower and dong quai
  • Designed for women's wellness needs
  • Convenient 90-capsule supply
  • Vegan-friendly and non-GMO ingredients
  • Gluten-free formulation
  • Free from dairy and soy
  • Easy-to-take capsule format

Equilife Progesterone Support for Women is an option for adults interested in exploring herbal products for menstrual or menopause-related wellness. However, the product's claims should be considered carefully because it has not been established that this formula directly raises progesterone levels or reliably treats menopause symptoms.

Important Safety Considerations

Herbal supplements can cause side effects and interact with medications. Black cohosh has been associated with rare cases of liver injury. Dong quai may increase bleeding risk, while coleus forskolin may affect blood pressure or interact with certain medicines. Avoid using this product during pregnancy or breastfeeding unless specifically advised by a qualified healthcare professional.

Women with liver conditions, hormone-sensitive medical conditions, unusual vaginal bleeding, or those taking hormonal medication should seek professional advice before use. Persistent menstrual irregularities or suspected low progesterone require medical evaluation rather than relying on supplements alone.

3. Life Extension

Life Extension
Life Extension Pregnenolone, 100 mg, Memory Support
Best Progesterone Support Supplements for Women

Life Extension Pregnenolone 100 mg is a supplement formulated to support memory, focus, and cognitive health. Pregnenolone is a steroid hormone precursor involved in several biological processes. The product provides 100 mg per serving and is gluten-free and non-GMO. Because pregnenolone can influence hormone pathways, consult a healthcare professional before use.

Life Extension Pregnenolone 100 mg is a hormone precursor supplement designed to support cognitive wellness, memory, focus, and overall well-being. Pregnenolone is a steroid hormone precursor involved in the body's production of other hormones, including progesterone, DHEA, testosterone, and estrogen. This supplement provides 100 mg of pregnenolone per capsule in a convenient 100-capsule bottle. The formula is unflavored and gluten-free, and the manufacturer states that its products are generally non-GMO and manufactured in the USA using internationally sourced ingredients.

Benefits

Life Extension Pregnenolone combines a single active ingredient with a convenient capsule format for adults researching hormone-related and cognitive wellness supplements.

  • Provides 100 mg pregnenolone per capsule
  • Supports cognitive wellness research interests
  • Designed for memory and focus support
  • Contains a steroid hormone precursor
  • Supports general hormone-related wellness research
  • Convenient single-ingredient capsule formula
  • Gluten-free supplement formulation
  • Unflavored capsules for easy use
  • Provides 100 capsules per bottle
  • Certificate of Analysis available, according to manufacturer

How It Works

Pregnenolone is produced naturally in the body from cholesterol and serves as a precursor in several steroid hormone pathways. It is also studied for its activity in the central nervous system. However, these biological roles do not establish that taking pregnenolone supplements improves memory, mood, or hormone balance in healthy adults.

  • Hormone precursor: Participates in pathways involved in producing other steroid hormones.
  • Cognitive research: Pregnenolone and related neurosteroids are studied for their roles in brain signaling.
  • Memory and focus: The supplement is marketed for cognitive support, but evidence of benefits from supplementation remains limited.
  • Mood-related pathways: Neurosteroids interact with systems involved in nervous system function, although clinical effects vary.
  • Daily capsule format: Provides a measured amount of pregnenolone in each capsule.

The effects of supplementation depend on individual health, hormone status, medications, and other factors. Pregnenolone should not be considered a proven treatment for memory problems, depression, or hormonal disorders.

Product Overview Table

FeatureDetails
BrandLife Extension
Product NamePregnenolone 100 mg
Supplement TypePregnenolone Supplement
Main IngredientPregnenolone
Strength100 mg per capsule
FormCapsules
Capsule Count100 Capsules
FlavorUnflavored
Diet TypeGluten-Free
Primary FocusCognitive and Hormone-Related Wellness
Product Benefits ListedHormone Balance
Quality InformationCertificate of Analysis available, according to the manufacturer
Manufacturing InformationManufactured in the USA with internationally sourced ingredients, according to the manufacturer

Why Choose Life Extension Pregnenolone

Life Extension Pregnenolone may interest adults researching supplements containing a single hormone precursor. Its clearly stated 100 mg strength, 100-capsule bottle, and manufacturer-provided quality documentation offer useful information for comparing products.

  • Single-ingredient pregnenolone formula
  • Provides 100 mg per capsule
  • Convenient 100-capsule bottle
  • Unflavored capsule format
  • Gluten-free formulation
  • Designed for adults researching hormone support
  • Marketed for memory and focus
  • Certificate of Analysis available
  • Established supplement brand

Life Extension Pregnenolone 100 mg is an option to consider when researching hormone precursor supplements. However, its marketed benefits for memory, focus, mood, and maintaining youthful hormone levels should not be interpreted as proven clinical outcomes.

Important Safety Considerations

Pregnenolone affects steroid hormone pathways, so supplementation may influence hormone-related processes and cause unwanted effects. Long-term safety data for supplemental pregnenolone are limited. People with hormone-sensitive conditions, those taking hormone therapy or hormonal medications, and anyone with a history of hormone-related disorders should consult a healthcare professional before use.

Pregnenolone is generally not appropriate during pregnancy or breastfeeding unless specifically directed by a qualified healthcare professional. Do not use it to self-treat memory changes, mood symptoms, or suspected low hormone levels without medical evaluation.

4. Birthright

Birthright
Birthright Revive Hormone Balance for Women – Progesterone Support
Natural Ways to Support Progesterone Production

Birthright Revive Hormone Balance for Women is a supplement marketed for menstrual cycle wellness, ovulation, energy, and menopause support. Its formula includes ingredients such as liver, magnesium, and red raspberry. The product is designed for women seeking nutritional support throughout different life stages, but evidence that it directly increases progesterone remains limited.

Birthright Revive Hormone Balance for Women is a multi-ingredient nutritional supplement designed to support women's wellness, menstrual cycle health, energy, and reproductive nutrition. This formula combines nutrients, including magnesium and vitamins, with ingredients such as liver and red raspberry, according to the product description. It comes in a bottle containing 180 capsules and is marketed for women across different life stages, including the reproductive years, postpartum period, and menopause. The product is labeled free from dairy, gluten, nuts, and soy.

Benefits

Birthright Revive combines nutritional ingredients and traditional botanicals to support women's everyday wellness and nutritional needs.

  • Supports women's nutritional wellness
  • Provides magnesium and essential vitamins
  • Includes red raspberry in its formula
  • Supports normal energy metabolism
  • Provides minerals for daily nutrition
  • Designed for menstrual wellness support
  • Formulated for women's reproductive nutrition
  • Offers 180 capsules per bottle
  • Free from dairy, gluten, nuts, and soy
  • Designed for adult women

How It Works

Birthright Revive combines vitamins, minerals, and other ingredients intended to complement women's nutritional needs. Nutrients such as magnesium, iron, zinc, and vitamins A, C, and E play established roles in normal bodily functions. Red raspberry is traditionally used in women's wellness products, although evidence for specific hormonal benefits is limited.

  • Magnesium: Supports normal muscle and nerve function.
  • Iron: Helps form hemoglobin, which carries oxygen in the blood.
  • Zinc: Contributes to immune function and normal cell division.
  • Vitamins A, C, and E: Support different functions, including immune health and protection from oxidative stress.
  • Selenium and copper: Help support essential metabolic and cellular processes.
  • Red raspberry: Traditionally used in women's wellness formulations, but strong evidence for increasing progesterone is lacking.
  • Liver ingredient: May provide nutrients, depending on the source and amount included.

These ingredients can contribute to nutritional wellness, but the product's complete formula has not been established as a treatment for low progesterone, infertility, irregular periods, or menopause symptoms.

Product Overview Table

FeatureDetails
BrandBirthright
Product NameRevive Hormone Balance for Women
Supplement TypeWomen's Nutritional Supplement
Main Ingredients ListedLiver, magnesium, red raspberry
Additional NutrientsVitamins A, B, C, E; selenium, iron, copper, zinc
FormCapsules
Capsule Count180 Capsules
FlavorRaspberry
Primary FocusWomen's Hormonal and Reproductive Wellness
Other Benefits ListedEnergy and immune support
Intended UsersAdults
Allergen InformationDairy-Free, Gluten-Free, Nut-Free, Soy-Free
PackageBottle

Why Choose Birthright Revive Hormone Balance

Birthright Revive may appeal to women seeking a multi-ingredient nutritional formula rather than a single vitamin or mineral supplement. Its combination of nutrients and traditional ingredients is marketed for women's wellness across different life stages.

  • Combines vitamins and essential minerals
  • Includes magnesium and red raspberry
  • Designed for women's nutritional needs
  • Provides a 180-capsule supply
  • Offers a multi-ingredient formula
  • Supports everyday nutritional wellness
  • Free from dairy and gluten
  • Free from nuts and soy
  • Designed for adult wellness routines

Birthright Revive Hormone Balance for Women is an option for adults researching supplements for general nutritional and reproductive wellness. Its vitamins and minerals may help meet nutritional needs, but there is insufficient evidence to conclude that this formula directly increases progesterone or restores fertility.

Important Safety Considerations

The supplied product description is incomplete, so the full ingredient list, quantities, and recommended serving size should be checked on the actual label before use.

Pregnancy and postpartum use require special care. A product marketed for pregnancy or postpartum wellness is not automatically suitable during these periods. Excessive intake of certain nutrients, including vitamin A in the retinol form, can be harmful during pregnancy. Consult an obstetrician or qualified healthcare professional before using this product if you are pregnant, breastfeeding, trying to conceive, or recently stopped hormonal birth control.

Women with heavy menstrual bleeding, persistent irregular cycles, suspected low progesterone, or fertility concerns should seek medical evaluation rather than relying on supplements alone.

5. VH Nutrition

VH Nutrition
VH Nutrition PROESTRO | Estrogen Support* Supplement for Women
Best Hormone Supplements for Female Wellness

VH Nutrition PROESTRO is an estrogen support supplement designed for women's hormonal wellness. It comes in a convenient 60-capsule format and is marketed to support healthy estrogen metabolism and hormonal balance. Women considering this product should review its complete ingredient list and consult a healthcare professional, particularly if they have hormone-sensitive conditions or take hormonal medication.

VH Nutrition PROESTRO is a women's wellness supplement formulated to support hormonal health and menopause-related wellness. This herbal blend features black cohosh, shatavari, vitex, dong quai, ginger root, and epimedium in an easy-to-swallow capsule format. The product comes in a bottle containing 60 unflavored capsules and is marketed to support mood, energy, and comfort during hormonal transitions. Its vegan formulation may appeal to women looking for a plant-based supplement as part of their daily wellness routine.

Benefits

VH Nutrition PROESTRO combines traditional botanical ingredients in a convenient formula designed for women's hormonal and menopausal wellness.

  • Supports women's hormonal wellness routines
  • Features black cohosh extract
  • Includes shatavari and vitex
  • Contains dong quai and ginger root
  • Provides a blend of botanical ingredients
  • Designed for menopause-related wellness support
  • Supports general mood and well-being
  • Convenient easy-to-swallow capsules
  • Vegan-friendly supplement formula
  • Provides 60 capsules per bottle

How It Works

VH Nutrition PROESTRO combines herbs traditionally used in women's wellness products. Some ingredients, particularly black cohosh, have been studied for their potential effects on menopause-related symptoms. However, evidence varies, and the effectiveness of individual ingredients cannot be assumed to apply to this complete formula.

  • Black cohosh: Studied for potential effects on hot flashes and other menopause symptoms, with mixed results.
  • Shatavari: Traditionally used in Ayurvedic wellness practices, although strong clinical evidence for hormonal benefits remains limited.
  • Vitex: Also known as chaste tree, it has been studied for certain menstrual symptoms.
  • Dong quai: Used in traditional herbal practices for women's health, but evidence for specific benefits is limited.
  • Ginger root: Commonly used for digestive wellness and other traditional applications.
  • Epimedium: A botanical ingredient used in traditional practices, with limited clinical evidence for women's hormonal wellness.

These ingredients have different properties and potential risks. Their combination does not establish that the product increases estrogen, balances hormones, or reliably relieves hot flashes, mood changes, or fatigue.

Product Overview Table

FeatureDetails
BrandVH Nutrition
Product NamePROESTRO Estrogen Support
Supplement TypeHerbal Supplement
Main Ingredient ListedBlack Cohosh
Additional IngredientsShatavari, vitex, dong quai, ginger root, epimedium
FormCapsules
Capsule Count60 Capsules
FlavorUnflavored
Diet TypeVegan
Primary FocusEstrogen and Menopause Support
Other Benefits MarketedMood and Energy Support
Intended UsersAdult Women
PackageBottle

Why Choose VH Nutrition PROESTRO

VH Nutrition PROESTRO may appeal to women comparing herbal supplements designed for menopause-related wellness. Its combination of several traditional botanicals offers an alternative to single-ingredient products, although suitability depends on individual health needs and the amounts of each ingredient.

  • Multi-ingredient botanical formula
  • Features black cohosh and shatavari
  • Includes vitex and dong quai
  • Contains ginger root and epimedium
  • Designed for women's wellness needs
  • Convenient 60-capsule bottle
  • Easy-to-swallow capsule format
  • Vegan-friendly formulation
  • Suitable for comparison with other herbal supplements

VH Nutrition PROESTRO is an option for women researching plant-based supplements for hormonal and menopausal wellness. However, the product's marketing claims should not be interpreted as proof that it raises estrogen levels or treats hormone-related conditions.

Important Safety Considerations

Herbal supplements can interact with medications and may not be suitable for everyone. Black cohosh has been associated with rare cases of liver injury. Dong quai may increase bleeding risk, while vitex can interact with certain hormonal or dopamine-related medications. The safety of combining these ingredients depends on their amounts and the user's health history.

Consult a healthcare professional before use if you take prescription medications, use hormonal contraception or hormone therapy, have liver disease or a hormone-sensitive condition, or are pregnant or breastfeeding. Seek medical advice for persistent hot flashes, unusual vaginal bleeding, or significant menstrual changes.

Progesterone is an important hormone that supports the menstrual cycle, reproductive health, and pregnancy. When progesterone levels are lower than expected, some women may experience irregular menstrual cycles, difficulty conceiving, or changes in menstrual patterns. The best supplements to increase progesterone are often discussed by women who want to support hormonal wellness naturally, especially during their reproductive years, perimenopause, or other periods of hormonal change. However, choosing the right supplement requires understanding the possible causes of low progesterone, the role of essential nutrients, and the difference between general wellness support and medically supervised hormone treatment.

Several supplements, including vitamin B6, magnesium, zinc, and selected herbal products, are marketed for women's hormonal health. Some may help address nutritional deficiencies or support normal bodily functions, but strong evidence that these supplements directly increase progesterone in humans is limited. Understanding their potential benefits and limitations can help women make informed decisions about reproductive health.

What Is Progesterone and Why Is It Important?

Progesterone is a steroid hormone produced mainly by the corpus luteum in the ovary after ovulation. During pregnancy, the placenta becomes a major source of progesterone. The hormone helps prepare the uterine lining for a possible pregnancy and supports the early stages of pregnancy. It also works alongside estrogen to regulate the menstrual cycle.

The best supplements to increase progesterone are often marketed for women experiencing menstrual irregularities, fertility concerns, or symptoms associated with hormonal changes. However, progesterone levels naturally fluctuate throughout the menstrual cycle, so one test result or symptom does not necessarily indicate a hormone deficiency.

How Progesterone Works in the Body

After ovulation, the corpus luteum produces progesterone during the luteal phase of the menstrual cycle. If pregnancy does not occur, progesterone levels decline, helping trigger menstruation. If pregnancy occurs, progesterone helps maintain the uterine environment during early pregnancy.

Progesterone also affects other tissues, including the breasts and nervous system. Its effects vary depending on the stage of the menstrual cycle, pregnancy status, age, and individual health.

What Can Cause Low Progesterone?

Progesterone levels may be lower when ovulation does not occur or when the timing of hormone production differs from what is expected. Possible contributing factors include:

  • Irregular or absent ovulation
  • Polycystic ovary syndrome (PCOS) in some women
  • Perimenopause and other reproductive transitions
  • Certain thyroid or reproductive health conditions
  • Significant calorie restriction or excessive exercise
  • Stress and disruptions to normal menstrual function
  • Some medications or treatments affecting ovulation

Symptoms such as irregular periods, difficulty conceiving, or unexpected bleeding can have several causes. A healthcare professional can help determine whether progesterone testing or further evaluation is appropriate.

Best Supplements to Increase Progesterone Naturally

The best supplements to increase progesterone are not necessarily those marketed as hormone boosters. Nutrients can support normal reproductive and metabolic functions, but correcting a deficiency is different from directly increasing progesterone production. The following ingredients are commonly discussed in women's hormonal wellness, along with what is known about their potential benefits.

1. Vitamin B6

Vitamin B6 is an essential nutrient involved in protein metabolism, nervous system function, and the production of certain neurotransmitters. It is commonly included in supplements marketed for premenstrual syndrome (PMS), mood changes, and women's hormonal wellness.

Although vitamin B6 is important for normal body functions, there is not enough strong evidence to establish it as a reliable way to increase progesterone levels. Some research has examined its use for PMS symptoms, but improving PMS symptoms does not necessarily mean progesterone levels have increased.

Potential benefits:

  • Supports normal nervous system function.
  • Helps the body metabolize protein.
  • Contributes to normal energy metabolism.
  • May help some PMS symptoms.

Food sources include poultry, fish, potatoes, bananas, and fortified cereals. Avoid high-dose vitamin B6 supplements unless recommended by a healthcare professional, because excessive long-term intake can damage peripheral nerves and cause tingling or numbness.

2. Magnesium

Magnesium is an essential mineral involved in muscle function, nerve signaling, energy production, and many other biological processes. It is commonly included in supplements designed to support relaxation, sleep, and menstrual wellness.

Magnesium is not proven to directly increase progesterone. However, meeting daily magnesium requirements supports general health, and some research suggests magnesium may help with selected PMS symptoms, although findings are mixed.

Potential benefits:

  • Supports normal muscle and nerve function.
  • Contributes to energy production.
  • Helps maintain normal physiological functions.
  • May support relief of some PMS symptoms.

Nuts, seeds, beans, whole grains, and leafy green vegetables are useful dietary sources. Supplemental magnesium may cause diarrhea and can interact with some medications. People with kidney disease should consult a healthcare professional before using it.

3. Zinc

Zinc is an essential mineral that supports immune function, cell division, wound healing, and normal reproductive processes. Because reproductive health depends on several nutrients, zinc is often included in women's wellness and fertility supplements.

However, zinc supplementation has not been established as a direct way to raise progesterone in women who already receive enough zinc from their diet. Its main value is helping prevent or correct inadequate intake.

Potential benefits:

  • Supports normal immune function.
  • Contributes to cell growth and repair.
  • Helps maintain normal reproductive function.
  • Supports healthy skin and wound healing.

Foods containing zinc include meat, shellfish, dairy products, legumes, seeds, and nuts. Taking excessive zinc for extended periods can cause copper deficiency and other problems. Check the amount in your supplement before combining it with a multivitamin.

4. Vitamin D

Vitamin D helps the body absorb calcium and maintain healthy bones. It also contributes to normal muscle function and immune health. Researchers have investigated associations between vitamin D status and reproductive conditions, including PCOS, but these findings do not prove that vitamin D supplementation increases progesterone.

For people with a vitamin D deficiency, supplementation may help restore adequate levels. The appropriate amount depends on dietary intake, individual risk factors, and medical advice.

Potential benefits:

  • Supports healthy bones and teeth.
  • Helps the body absorb calcium.
  • Contributes to normal muscle function.
  • Helps correct vitamin D deficiency.

Food sources include oily fish, egg yolks, and fortified foods. Vitamin D supplements should be used responsibly because excessive intake can cause high blood calcium levels and kidney-related complications.

5. Vitex or Chasteberry

Vitex agnus-castus, commonly called chasteberry, is a botanical ingredient used in some women's wellness supplements. It is traditionally associated with menstrual health and is sometimes marketed for progesterone support.

Some studies have investigated vitex for PMS symptoms, but the quality of evidence varies. Its effects on hormone-related pathways do not establish that it reliably increases progesterone or treats infertility.

Potential benefits being studied:

  • Support for selected PMS symptoms.
  • Potential effects on menstrual discomfort.
  • Possible effects on hormone-related signaling.

Vitex may interact with hormonal medications and medicines that affect dopamine pathways. Avoid self-treating suspected low progesterone with chasteberry, particularly if you are pregnant, breastfeeding, undergoing fertility treatment, or using hormonal contraception.

6. Vitamin C

Vitamin C is an antioxidant nutrient that supports collagen production, wound healing, and normal immune function. It is found in many fruits and vegetables and is sometimes included in fertility and women's wellness supplements.

Although vitamin C is important for general health, evidence is insufficient to recommend it as a reliable progesterone-boosting supplement. Correcting inadequate vitamin C intake supports normal nutrition but does not guarantee changes in reproductive hormones.

Potential benefits:

  • Supports normal immune function.
  • Helps the body produce collagen.
  • Improves absorption of iron from plant foods.
  • Contributes to antioxidant protection.

Citrus fruits, kiwi, strawberries, peppers, and broccoli are good sources. High-dose vitamin C may cause digestive discomfort and may be unsuitable for some people with a history of kidney stones.

7. Myo-Inositol

Myo-inositol is a compound involved in cellular signaling. It is commonly used in women's wellness products, particularly those marketed for PCOS, insulin-related health, and menstrual cycle support.

Research has examined myo-inositol and D-chiro-inositol in women with PCOS. Some studies report improvements in selected metabolic or reproductive outcomes, but the evidence is not conclusive for all outcomes or formulations. Inositol is not an established direct progesterone booster.

Potential benefits being studied:

  • Support for selected metabolic outcomes in PCOS.
  • Potential improvements in menstrual regularity.
  • Support for normal cellular signaling.
  • Possible effects on ovarian function.

Products such as MEDCHOICE Myo-Inositol 40:1 and Optify Myo-Inositol and D-Chiro Inositol include these ingredients alongside nutrients such as folate and vitamin D. Women considering these products should review the ingredient amounts and discuss their suitability with a healthcare professional, especially when trying to conceive.

8. Herbal Blends for Women's Hormonal Wellness

Some supplements combine herbs such as black cohosh, passionflower, dong quai, red raspberry, or shatavari. These products are marketed for menstrual comfort, menopause-related symptoms, mood, or general reproductive wellness.

However, herbal ingredients do not all work in the same way. Evidence for some uses is limited, and a blend marketed for progesterone support is not necessarily proven to increase progesterone levels.

For example, Equilife Progesterone Support includes black cohosh and passionflower, while Birthright Revive Hormone Balance contains ingredients such as magnesium and red raspberry, according to their product descriptions. These formulations should be evaluated by their ingredients, doses, safety, and available evidence rather than their marketing names.

Important: Herbal supplements may interact with prescription medicines or cause side effects. Black cohosh has been associated with rare cases of liver injury, and some botanicals may not be appropriate during pregnancy or fertility treatment.

How to Choose the Right Progesterone Support Supplement

Choosing the best supplements to increase progesterone starts with understanding your health needs rather than purchasing the product with the strongest marketing claims. Nutritional deficiencies, irregular ovulation, thyroid problems, and reproductive transitions can require different approaches.

Check the Ingredients and Dosage

Always review the Supplement Facts panel before buying a product. Look for the amount of each active ingredient, the recommended serving size, potential allergens, and any warnings.

A supplement with many ingredients is not necessarily more effective than a simpler formula. Products that combine multiple herbs, vitamins, minerals, and hormone-related ingredients may also increase the risk of side effects and interactions.

Look for Quality Testing

Choose supplements from manufacturers that provide clear ingredient information and appropriate quality-control details. Independent testing can help verify ingredient identity and assess contamination risks, but it does not prove that a product increases progesterone.

Avoid products that promise guaranteed fertility, immediate hormone balance, or a cure for reproductive conditions.

Consider Your Individual Needs

The right supplement depends on your diet, medical history, symptoms, and reproductive goals. For example, someone with a confirmed vitamin deficiency may benefit from correcting it, while someone experiencing irregular periods may need evaluation for an underlying condition.

If you are trying to conceive, consult a healthcare professional before using fertility or hormone support supplements. Nutritional products should complement appropriate medical care rather than replace it.

Natural Ways to Support Healthy Progesterone Function

Supplements to increase progesterone receive considerable attention, but everyday habits also matter for overall reproductive health. Maintaining adequate nutrition, sufficient sleep, and balanced physical activity can support normal bodily functions.

Eat a Balanced Diet

Include a variety of vegetables, fruits, whole grains, healthy fats, and protein sources in your daily meals. Foods containing zinc, magnesium, vitamin B6, and other essential nutrients help meet normal nutritional requirements.

Healthy fats from foods such as nuts, seeds, olive oil, and fish contribute to a balanced diet. However, eating a particular food does not guarantee increased progesterone production.

Maintain Adequate Energy Intake

Severely restricting calories or exercising excessively without sufficient nutrition can interfere with menstrual function and ovulation in some women.

Aim for regular, balanced meals that provide enough energy for your daily activities. If your periods become irregular after substantial weight loss or increased exercise, seek medical advice.

Prioritize Sleep and Stress Management

Consistent sleep and stress-management habits support overall health. Consider maintaining a regular bedtime, engaging in moderate physical activity, and practising relaxation techniques.

Although stress can influence reproductive function, persistent symptoms should not automatically be attributed to stress or treated with supplements alone.

When Should You Get Your Progesterone Levels Checked?

If you suspect low progesterone, a healthcare professional can help determine whether testing is appropriate. Progesterone levels change throughout the menstrual cycle, so the timing of a blood test matters.

Testing may be considered in situations involving irregular ovulation, fertility concerns, or certain pregnancy-related questions. A single result may not provide a complete picture, and interpretation depends on the reason for testing and the timing of the sample.

Seek medical advice if you experience:

  • Repeatedly irregular or absent periods.
  • Difficulty conceiving.
  • Unexplained vaginal bleeding.
  • Persistent menstrual changes.
  • Symptoms suggesting a thyroid or other hormonal condition.

If you are pregnant and experience vaginal bleeding or significant abdominal pain, seek prompt medical assessment. Severe pain, fainting, or heavy bleeding may require emergency care.

Final Thoughts:

The best supplements to increase progesterone are not necessarily the products marketed specifically for hormone balance. Vitamin B6, magnesium, zinc, and vitamin D help support normal physiological functions, while myo-inositol and selected herbal ingredients have been studied for particular reproductive or menstrual concerns. However, evidence that these supplements directly increase progesterone remains limited.

The most effective approach is to understand the cause of your symptoms, maintain a balanced diet, address confirmed nutritional deficiencies, and seek medical guidance when necessary. If you have irregular periods, difficulty conceiving, or concerns about low progesterone, a healthcare professional can help determine whether testing or treatment is appropriate.

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Peter K. Attia

Peter K. Attia, MD, is an ABMS board-certified physician specializing in longevity, metabolic health, and performance optimization. With a background in surgical oncology and expertise in nutrition and exercise physiology, Dr. Attia is committed to helping individuals extend both lifespan and health span. His groundbreaking research on insulin resistance, fat loss, and physical performance provides cutting-edge insights for achieving optimal health and overall wellness, making him a leading authority in the field.

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